PROteolysis Targeting Chimeras: A new cutting‐edge nanomedicine for colorectal cancer

• Main Authors: Swastika Maitra (Author), Nobendu Mukerjee (Author), Dattatreya Mukherjee (Author), Arabinda Ghosh (Author), Athanasios T. Alexiou (Author)
• Format: Book
• Published: Wiley, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Colorectal cancer (CRC) is a prevalent malignancy with a high mortality rate, necessitating innovative treatment strategies. PROTACs (PROteolysis Targeting Chimeras) represent a promising therapeutic approach by targeting and degrading oncogenic proteins via the ubiquitin‐proteasome pathway...