Curcumin-Loaded Solid Lipid Nanoparticles Bypass P-Glycoprotein Mediated Doxorubicin Resistance in Triple Negative Breast Cancer Cells

• Main Authors: Gamal-Eldein Fat (Author), Elena Gazzano (Author), Daniela Chirio (Author), Ahmed Ragab Hamed (Author), Dimas Carolina Belisario (Author), Carlo Zuddas (Author), Elena Peira (Author), Barbara Rolando (Author), Joanna Kopecka (Author), Mohamed Assem Said Marie (Author), Simona Sapino (Author), Sohair Ramadan Fahmy (Author), Marina Gallarate (Author), Abdel-Hamid Zaki (Author), Chiara Riganti (Author)
• Format: Book
• Published: MDPI AG, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Multidrug resistance (MDR) is a critical hindrance to the success of cancer chemotherapy. The main thing responsible for MDR phenotypes are plasma-membranes associated with adenosine triphosphate (ATP) Binding Cassette (ABC) drug efflux transporters, such as the P-glycoprotein (Pgp) transporter that...