The SP1-12LOX axis promotes chemoresistance and metastasis of ovarian cancer

• Main Authors: Qi Zhang (Author), Guifang Yan (Author), Juan Lei (Author), Yu Chen (Author), Ting Wang (Author), Juan Gong (Author), Yong Zhou (Author), Huakan Zhao (Author), Hao Chen (Author), Yu Zhou (Author), Lei Wu (Author), Jiangang Zhang (Author), Xiao Zhang (Author), Jingchun Wang (Author), Yongsheng Li (Author)
• Format: Book
• Published: BMC, 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Ovarian cancer is the most lethal gynecologic cancer. Chemoresistance, especially platinum-resistance, is closely related to metastasis of ovarian cancer, however, the molecular basis by which links chemoresistance and metastasis remains vague. Disordered arachidonic acid (AA) me...