Promoter Targeting shRNA Suppresses HIV-1 Infection In vivo Through Transcriptional Gene Silencing

• Glavni autori: Kazuo Suzuki (Autor), Shinichiro Hattori (Autor), Katherine Marks (Autor), Chantelle Ahlenstiel (Autor), Yosuke Maeda (Autor), Takaomi Ishida (Autor), Michelle Millington (Autor), Maureen Boyd (Autor), Geoff Symonds (Autor), David A Cooper (Autor), Seiji Okada (Autor), Anthony D Kelleher (Autor)
• Format: Knjiga
• Izdano: Elsevier, 2013-01-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Despite prolonged and intensive application, combined antiretroviral therapy cannot eradicate human immunodeficiency virus (HIV)-1 because it is harbored as a latent infection, surviving for long periods of time. Alternative approaches are required to overcome the limitations of current therapy. We...