Planarians as an In Vivo Experimental Model for the Study of New Radioprotective Substances

• Main Authors: Artem M. Ermakov (Author), Kristina A. Kamenskikh (Author), Olga N. Ermakova (Author), Artem S. Blagodatsky (Author), Anton L. Popov (Author), Vladimir K. Ivanov (Author)
• Format: Book
• Published: MDPI AG, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ionising radiation causes the death of the most actively dividing cells, thus leading to depletion of the stem cell pool. Planarians are invertebrate flatworms that are unique in that their stem cells, called neoblasts, constantly replace old, damaged, or dying cells. Amenability to efficient RNAi t...