Impact of Drug Loading Method on Drug Release from 3D-Printed Tablets Made from Filaments Fabricated by Hot-Melt Extrusion and Impregnation Processes

• Main Authors: Kasitpong Thanawuth (Author), Lalinthip Sutthapitaksakul (Author), Srisuda Konthong (Author), Supakij Suttiruengwong (Author), Kampanart Huanbutta (Author), Crispin R. Dass (Author), Pornsak Sriamornsak (Author)
• Format: Book
• Published: MDPI AG, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The purpose of this study was to investigate the impact of the drug loading method on drug release from 3D-printed tablets. Filaments comprising a poorly water-soluble model drug, indomethacin (IND), and a polymer, polyvinyl alcohol (PVA), were prepared by hot-melt extrusion (HME) and compared with...