Patient-Specific iPSC-Based Models of Huntington's Disease as a Tool to Study Store-Operated Calcium Entry Drug Targeting

• Main Authors: Vladimir Vigont (Author), Evgeny Nekrasov (Author), Alexey Shalygin (Author), Konstantin Gusev (Author), Sergey Klushnikov (Author), Sergey Illarioshkin (Author), Maria Lagarkova (Author), Sergey L. Kiselev (Author), Elena Kaznacheyeva (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Neurodegenerative pathologies are among the most serious and socially significant problems of modern medicine, along with cardiovascular and oncological diseases. Several attempts have been made to prevent neuronal death using novel drugs targeted to the cell calcium signaling machinery, but the lac...