Maintenance over Time of the Effect Produced by Esmolol on the Structure and Function of Coronary Arteries in Hypertensive Heart Diseases

• Hauptverfasser: Raquel Martín-Oropesa (Verfasst von), Pilar Rodríguez-Rodríguez (Verfasst von), Laia Pazó-Sayós (Verfasst von), Ana Arnalich-Montiel (Verfasst von), Silvia Magdalena Arribas (Verfasst von), Maria Carmen González (Verfasst von), Begoña Quintana-Villamandos (Verfasst von)
• Format: Buch
• Veröffentlicht: MDPI AG, 2022-10-01T00:00:00Z.
• Schlagworte: article
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We previously observed that esmolol treatment for 48 h reduced vascular lesions in spontaneously hypertensive rats (SHRs). Therefore, we investigated whether this beneficial effect is persistent after withdrawal. Fourteen-month-old SHRs (SHR-Es) were treated with esmolol (300 μg/kg/min) or a vehicle...