Targeting of the COX-2/PGE2 axis enhances the antitumor activity of T7 peptide in vitro and in vivo

• Main Authors: Jianrong Yang (Author), Jingtao Zhong (Author), Mi Zhou (Author), Yinghong Zhou (Author), Peng Xiu (Author), Feng Liu (Author), Fuhai Wang (Author), Zelun Li (Author), Yuntian Tang (Author), Yuanyuan Chen (Author), Siyang Yao (Author), Tao Huang (Author), Tianqi Liu (Author), Xiaofeng Dong (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

T7 peptide is considered as an antiangiogenic polypeptide. The presents study aimed to further detect the antiangiogenic mechanisms of T7 peptide and determine whether combining T7 peptide and meloxicam (COX-2/PGE2 specific inhibitor) could offer a better therapy to combat hepatocellular carcinoma (...