TGF-β1/Smads and miR-21 in Renal Fibrosis and Inflammation

• Main Authors: Agnieszka Loboda (Author), Mateusz Sobczak (Author), Alicja Jozkowicz (Author), Jozef Dulak (Author)
• Formato: Livro
• Publicado em: Hindawi Limited, 2016-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Renal fibrosis, irrespective of its etiology, is a final common stage of almost all chronic kidney diseases. Increased apoptosis, epithelial-to-mesenchymal transition, and inflammatory cell infiltration characterize the injured kidney. On the molecular level, transforming growth factor-β1 (TGF-β1)-S...