The RGD region of bone sialoprotein affects metabolic activity in mice

The RGD region of bone sialoprotein affects metabolic activity in mice

IntroductionBone sialoprotein (BSP) is a key regulator of mineralized tissue formation. Previously, we generated BSP-KAE knock-in mice (KAEKI mice) by substituting a non-function KAE (lysine-alanine-glutamic acid) for the integrin-binding RGD (arginine-glycine-aspartic acid) sequence and reported a...

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Main Authors: Karin Nagasaki (Author), Atsuhiro Nagasaki (Author), Jocelyn M. Taylor (Author), Bernice D. Kear (Author), Yinyan Ma (Author), Martha J. Somerman (Author), Oksana Gavrilova (Author)
Format: Book
Published: Frontiers Media S.A., 2023-03-01T00:00:00Z.
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