The RGD region of bone sialoprotein affects metabolic activity in mice

• Główni autorzy: Karin Nagasaki (Autor), Atsuhiro Nagasaki (Autor), Jocelyn M. Taylor (Autor), Bernice D. Kear (Autor), Yinyan Ma (Autor), Martha J. Somerman (Autor), Oksana Gavrilova (Autor)
• Format: Książka
• Wydane: Frontiers Media S.A., 2023-03-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

IntroductionBone sialoprotein (BSP) is a key regulator of mineralized tissue formation. Previously, we generated BSP-KAE knock-in mice (KAEKI mice) by substituting a non-function KAE (lysine-alanine-glutamic acid) for the integrin-binding RGD (arginine-glycine-aspartic acid) sequence and reported a...