Improving the integrity and reproducibility of research that uses antibodies: a technical, data sharing, behavioral and policy challenge

• Autori principali: M. Biddle (Autore), P. Stylianou (Autore), M. Rekas (Autore), A. Wright (Autore), J. Sousa (Autore), D. Ruddy (Autore), M. I. Stefana (Autore), K. Kmiecik (Autore), A. Bandrowski (Autore), R.A. Kahn (Autore), C. Laflamme (Autore), E. M. Krockow (Autore), H.S. Virk (Autore)
• Natura: Libro
• Pubblicazione: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

ABSTRACTAntibodies are one of the most important reagents used in biomedical and fundamental research, used to identify, and quantify proteins, contribute to knowledge of disease mechanisms, and validate drug targets. Yet many antibodies used in research do not recognize their intended target, or re...