Cannabidiol exhibits potent anti-cancer activity against gemcitabine-resistant cholangiocarcinoma via ER-stress induction in vitro and in vivo

• Main Authors: Thatsanapong Pongking (Author), Phonpilas Thongpon (Author), Kitti Intuyod (Author), Sirinapha Klungsaeng (Author), Raynoo Thanan (Author), Apisit Chaidee (Author), Naruechar Charoenram (Author), Suppakrit Kongsintaweesuk (Author), Chadamas Sakonsinsiri (Author), Kulthida Vaeteewoottacharn (Author), Somchai Pinlaor (Author), Porntip Pinlaor (Author)
• Format: Book
• Published: BMC, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Failure of treatment with gemcitabine in most cholangiocarcinoma (CCA) patients is due to drug resistance. The therapeutic potential of natural plant secondary compounds with minimal toxicity, such as cannabidiol (CBD), is a promising line of investigation in gemcitabine-resistan...