Histone deacetylase activity is decreased in peripheral blood monocytes in patients with COPD

• Main Authors: Chen Yanwei (Author), Huang Ping (Author), Ai Wen (Author), Li Xiaoli (Author), Guo Wei (Author), Zhang Jingnong (Author), Yang Jiong (Author)
• Format: Book
• Published: BMC, 2012-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Histone deacetylase (HDAC) is an enzyme that regulates chromatin structure and inflammatory gene expression. In patients with chronic obstructive pulmonary disease (COPD), while accumulating evidence indicates that the activity of HD...