Novel Ordered Stepped-Wedge Cluster Trial Designs for Detecting Ebola Vaccine Efficacy Using a Spatially Structured Mathematical Model.
BACKGROUND:During the 2014 Ebola virus disease (EVD) outbreak, policy-makers were confronted with difficult decisions on how best to test the efficacy of EVD vaccines. On one hand, many were reluctant to withhold a vaccine that might prevent a fatal disease from study participants randomized to a co...
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| Main Authors: | , , , |
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| Format: | Book |
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Public Library of Science (PLoS),
2016-08-01T00:00:00Z.
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| Call Number: |
A1234.567 |
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| Copy 1 | Available |