Cloning, characterization, and inhibition of the novel β-carbonic anhydrase from parasitic blood fluke, Schistosoma mansoni

Schistosoma mansoni is an intestinal parasite with one β-class carbonic anhydrase, SmaBCA. We report the sequence enhancing, production, catalytic activity, and inhibition results of the recombinant SmaBCA. It showed significant catalytic activity on CO2 hydration in vitro with kcat 1.38 × 105 s−1 a...

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Main Authors: Susanna Haapanen (Author), Andrea Angeli (Author), Martti Tolvanen (Author), Reza Zolfaghari Emameh (Author), Claudiu T. Supuran (Author), Seppo Parkkila (Author)
Format: Book
Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
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