Metal‐HisTag coordination for remote loading of very small quantities of biomacromolecules into PLGA microspheres

• Autores principales: Jason Albert (Autor), Rae Sung Chang (Autor), George A. Garcia (Autor), Steven P. Schwendeman (Autor)
• Formato: Libro
• Publicado: Wiley, 2022-05-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Abstract Challenges to discovery and preclinical development of long‐acting release systems for protein therapeutics include protein instability, use of organic solvents during encapsulation, specialized equipment and personnel, and high costs of proteins. We sought to overcome these issues by combi...