Three-Dimensional Spheroids as In Vitro Preclinical Models for Cancer Research

• Hoofdauteurs: Bárbara Pinto (Auteur), Ana C. Henriques (Auteur), Patrícia M. A. Silva (Auteur), Hassan Bousbaa (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2020-12-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Most cancer biologists still rely on conventional two-dimensional (2D) monolayer culture techniques to test in vitro anti-tumor drugs prior to in vivo testing. However, the vast majority of promising preclinical drugs have no or weak efficacy in real patients with tumors, thereby delaying the discov...