Increased Expression of Delta-like Ligand 4 in Mycosis Fungoides

• Main Authors: Hikari Boki (Author), Tomomitsu Miyagaki (Author), Yuki Shono (Author), Hiroaki Kamijo (Author), Tomonori Oka (Author), Hiraku Suga (Author), Yoshihide Asano (Author), Makoto Sugaya (Author), Shinichi Sato (Author)
• Format: Book
• Published: Medical Journals Sweden, 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In many malignancies, dysregulation of the Notch pathways, composed of 4 Notch receptors (Notch1-4) and 5 Notch ligands (Jagged1-2, Delta-like ligand-1, 3-4), is associated with their development. In mycosis fungoides, interaction between Notch1 and Jagged1 is known to activate the Notch pathways an...