Zebrafish etv7 regulates red blood cell development through the cholesterol synthesis pathway

• Main Authors: Anita M. Quintana (Author), Fabrizio Picchione (Author), Ramon I. Klein Geltink (Author), Michael R. Taylor (Author), Gerard C. Grosveld (Author)
• Format: Book
• Published: The Company of Biologists, 2014-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ETV7 is a human oncoprotein that cooperates with Eμ-MYC to promote pre-B-cell leukemia in mice. It is normally expressed in the bone marrow and fetal liver and is upregulated in primary leukemia, suggesting that it is involved in proper hematopoiesis and leukemogenesis. ETV7 has been deleted in most...