An ex-vivo human intestinal model to study Entamoeba histolytica pathogenesis.

• Main Authors: Devendra Bansal (Author), Patrick Ave (Author), Sophie Kerneis (Author), Pascal Frileux (Author), Olivier Boché (Author), Anne Catherine Baglin (Author), Geneviève Dubost (Author), Anne-Sophie Leguern (Author), Marie-Christine Prevost (Author), Rivka Bracha (Author), David Mirelman (Author), Nancy Guillén (Author), Elisabeth Labruyère (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2009-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Amoebiasis (a human intestinal infection affecting 50 million people every year) is caused by the protozoan parasite Entamoeba histolytica. To study the molecular mechanisms underlying human colon invasion by E. histolytica, we have set up an ex vivo human colon model to study the early steps in amo...