Trypanosoma cruzi IIc: phylogenetic and phylogeographic insights from sequence and microsatellite analysis and potential impact on emergent Chagas disease.

• Main Authors: Martin S Llewellyn (Author), Michael D Lewis (Author), Nidia Acosta (Author), Matthew Yeo (Author), Hernan J Carrasco (Author), Maikell Segovia (Author), Jorge Vargas (Author), Faustino Torrico (Author), Michael A Miles (Author), Michael W Gaunt (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2009-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Trypanosoma cruzi, the etiological agent of Chagas disease, is highly genetically diverse. Numerous lines of evidence point to the existence of six stable genetic lineages or DTUs: TcI, TcIIa, TcIIb, TcIIc, TcIId, and TcIIe. Molecular dating suggests that T. cruzi is likely to have been an endemic i...