Anticonvulsant evaluation of 2-pyrazolines carrying naphthyl moiety: An insight into synthesis and molecular docking study

• Main Authors: Birjees Nusrat (Author), Nadeem Siddiqui (Author), Meeta Sahu (Author), Mohd. Javed Naim (Author), Mohammad Shahar Yar (Author), Ruhi Ali (Author), Alam Ozair (Author)
• Format: Book
• Published: Universidade de São Paulo.
• Subjects: article
• Online Access: Connect to this object online.

A series of N-substituted-3-(napthalen-2-yl)-5-substituted phenyl-4,5-dihydropyrazole-1-carbothioamide derivatives (4a-n) were synthesized with the view of structural requirements of pharmacophore for potential anticonvulsant agents. The synthesized compounds were assayed intraperitoneally (i.p.) an...