Lipidomics Profiling of Metformin-Induced Changes in Obesity and Type 2 Diabetes Mellitus: Insights and Biomarker Potential

• Main Authors: Muhammad Mujammami (Author), Shereen M. Aleidi (Author), Adriana Zardini Buzatto (Author), Awad Alshahrani (Author), Reem H. AlMalki (Author), Hicham Benabdelkamel (Author), Mohammed Al Dubayee (Author), Liang Li (Author), Ahmad Aljada (Author), Anas M. Abdel Rahman (Author)
• Format: Book
• Published: MDPI AG, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Metformin is the first-line oral medication for treating type 2 diabetes mellitus (T2DM). In the current study, an untargeted lipidomic analytical approach was used to investigate the alterations in the serum lipidome of a cohort of 89 participants, including healthy lean controls and obese diabetic...