Case Report: IL-21 and Bcl-6 Regulate the Proliferation and Secretion of Tfh and Tfr Cells in the Intestinal Germinal Center of Patients With Inflammatory Bowel Disease

• Main Authors: Youguang Yang (Author), Xiaodan Lv (Author), Lingling Zhan (Author), Lan Chen (Author), Hui Jin (Author), Xinping Tang (Author), Qingqing Shi (Author), Qiyuan Zou (Author), Jiqiao Xiang (Author), WeiWei Zhang (Author), Zhaojing Zeng (Author), Haixing Jiang (Author), Xiaoping Lv (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: This study aimed to investigate the effect of interleukin (IL)-21 and B cell lymphoma protein-6 on germinal center follicular helper T (Tfh) cells and follicular regulatory T (Tfr) cells and its relationship with the clinical features of inflammatory bowel disease (IBD).Methods: The expre...