An Improved Enzyme-Linked Focus Formation Assay Revealed Baloxavir Acid as a Potential Antiviral Therapeutic Against Hantavirus Infection

• Main Authors: Chuantao Ye (Author), Dan Wang (Author), He Liu (Author), Hongwei Ma (Author), Yangchao Dong (Author), Min Yao (Author), Yuan Wang (Author), Hui Zhang (Author), Liang Zhang (Author), Linfeng Cheng (Author), Zhikai Xu (Author), Yingfeng Lei (Author), Fanglin Zhang (Author), Wei Ye (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hantaviruses, etiologic pathogens responsible for two severe human diseases, exist in areas ranging from Eurasia to America and remain global public health concerns. Conventionally, plaque formation assays have been used for hantavirus titering. However, hantaviruses replicate slowly within cells an...