A novel bi-alleleic DDX41 mutations in B-cell lymphoblastic leukemia: case report

• Main Authors: Woo Yong Shin (Author), Seug Yun Yoon (Author), Rojin Park (Author), Jung-Ah Kim (Author), Ho Hyun Song (Author), Hae In Bang (Author), Jong-Ho Won (Author), Jieun Kim (Author)
• Format: Book
• Published: BMC, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The germline mutations of DDX41, also known as DEAD box RNA helicase 41, have been found in about 1.5% of myeloid neoplasms (MNs). Development of MDS/AML is relatively common in germline DDX41 mutations. However, a variety of hematological malignancies (HMs) have been reported. C...