CD8 cells of patients with diffuse cutaneous leishmaniasis display functional exhaustion: the latter is reversed, in vitro, by TLR2 agonists.

CD8 cells of patients with diffuse cutaneous leishmaniasis display functional exhaustion: the latter is reversed, in vitro, by TLR2 agonists.

Leishmania mexicana (Lm) causes localized (LCL) and diffuse (DCL) cutaneous leishmaniasis. DCL patients have a poor cellular immune response leading to chronicity. It has been proposed that CD8 T lymphocytes (CD8) play a crucial role in infection clearance, although the role of CD8 cytotoxicity in d...

Full description

Saved in:
Bibliographic Details
Main Authors: Joselín Hernández-Ruiz (Author), Norma Salaiza-Suazo (Author), Georgina Carrada (Author), Sofía Escoto (Author), Adriana Ruiz-Remigio (Author), Yvonne Rosenstein (Author), Alejandro Zentella (Author), Ingeborg Becker (Author)
Format: Book
Published: Public Library of Science (PLoS), 2010-01-01T00:00:00Z.
Subjects:
article
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

Connect to this object online.

3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
Copy 1 Available

Similar Items