Identification of α-glucosidase inhibitors from Clinacanthus nutans leaf extract using liquid chromatography-mass spectrometry-based metabolomics and protein-ligand interaction with molecular docking

• Hauptverfasser: Suganya Murugesu (Verfasst von), Zalikha Ibrahim (Verfasst von), Qamar Uddin Ahmed (Verfasst von), Bisha Fathamah Uzir (Verfasst von), Nik Idris Nik Yusoff (Verfasst von), Vikneswari Perumal (Verfasst von), Faridah Abas (Verfasst von), Khozirah Shaari (Verfasst von), Alfi Khatib (Verfasst von)
• Format: Buch
• Veröffentlicht: Elsevier, 2019-04-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

The present study used in vitro and in silico techniques, as well as the metabolomics approach to characterise α-glucosidase inhibitors from different fractions of Clinacanthus nutans. C. nutans is a medicinal plant belonging to the Acanthaceae family, and is traditionally used to treat diabetes in...