Identification of α-glucosidase inhibitors from Clinacanthus nutans leaf extract using liquid chromatography-mass spectrometry-based metabolomics and protein-ligand interaction with molecular docking

• Main Authors: Suganya Murugesu (Author), Zalikha Ibrahim (Author), Qamar Uddin Ahmed (Author), Bisha Fathamah Uzir (Author), Nik Idris Nik Yusoff (Author), Vikneswari Perumal (Author), Faridah Abas (Author), Khozirah Shaari (Author), Alfi Khatib (Author)
• Format: Book
• Published: Elsevier, 2019-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The present study used in vitro and in silico techniques, as well as the metabolomics approach to characterise α-glucosidase inhibitors from different fractions of Clinacanthus nutans. C. nutans is a medicinal plant belonging to the Acanthaceae family, and is traditionally used to treat diabetes in...