Uncovering the effects and molecular mechanism of Astragalus membranaceus (Fisch.) Bunge and its bioactive ingredients formononetin and calycosin against colon cancer: An integrated approach based on network pharmacology analysis coupled with experimental validation and molecular docking

• Main Authors: Yu Hu (Author), Wenjuan Zhai (Author), Duanling Tan (Author), Haipeng Chen (Author), Guiyu Zhang (Author), Xuanjing Tan (Author), Yuting Zheng (Author), Wenhui Gao (Author), Yijie Wei (Author), Jinjun Wu (Author), Xin Yang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Colon cancer is a highly malignant cancer with poor prognosis. Astragalus membranaceus (Fisch.) Bunge (Huang Qi in Chinese, HQ), a well-known Chinese herbal medicine and a popular food additive, possesses various biological functions and has been frequently used for clinical treatment of colon cance...