A novel pentapeptide targeting integrin β3-subunit inhibits platelet aggregation and its application in rat for thrombosis prevention

• Main Authors: Qingrong eQu (Author), Naifeng eLiu (Author), Guoqiu eWu (Author), Xiaobo eFan (Author), Yamin eLiu (Author), Xuejiao eYan (Author)
• Format: Bog
• Udgivet: Frontiers Media S.A., 2016-03-01T00:00:00Z.
• Fag: article
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Background: Antiplatelet therapy plays a pivotal role in the prevention and treatment of thrombotic diseases. We reported the screening of P1C as a novel integrin-binding peptide from the C-terminal of connective tissue growth factor. Primary study indicated that P1C has potential against platelet a...