IVIVC Assessment of Two Mouse Brain Endothelial Cell Models for Drug Screening

IVIVC Assessment of Two Mouse Brain Endothelial Cell Models for Drug Screening

Since most preclinical drug permeability assays across the blood-brain barrier (BBB) are still evaluated in rodents, we compared an in vitro mouse primary endothelial cell model to the mouse b.End3 and the acellular parallel artificial membrane permeability assay (PAMPA) models for drug screening pu...

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Main Authors: Ina Puscas (Author), Florian Bernard-Patrzynski (Author), Martin Jutras (Author), Marc-André Lécuyer (Author), Lyne Bourbonnière (Author), Alexandre Prat (Author), Grégoire Leclair (Author), V. Gaëlle Roullin (Author)
Format: Book
Published: MDPI AG, 2019-11-01T00:00:00Z.
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3rd Floor Main Library

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