The Dynamics of Compound, Transcript, and Protein Effects After Treatment With 2OMePS Antisense Oligonucleotides in mdx Mice

The Dynamics of Compound, Transcript, and Protein Effects After Treatment With 2OMePS Antisense Oligonucleotides in mdx Mice

Antisense-mediated exon skipping is currently in clinical development for Duchenne muscular dystrophy (DMD) to amend the consequences of the underlying genetic defect and restore dystrophin expression. Due to turnover of compound, transcript, and protein, chronic treatment with effector molecules (a...

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Main Authors: Ingrid E C Verhaart (Author), Laura van Vliet-van den Dool (Author), Jessica A Sipkens (Author), Sjef J de Kimpe (Author), Ingrid G M Kolfschoten (Author), Judith C T van Deutekom (Author), Lia Liefaard (Author), Jim E Ridings (Author), Steve R Hood (Author), Annemieke Aartsma-Rus (Author)
Format: Book
Published: Elsevier, 2014-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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