Characterization of Formononetin Sulfonation in SULT1A3 Overexpressing HKE293 Cells: Involvement of Multidrug Resistance-Associated Protein 4 in Excretion of Sulfate

• Main Authors: Fanye Liu (Author), Shuhua Pei (Author), Wenqi Li (Author), Xiao Wang (Author), Chao Liang (Author), Ruohan Yang (Author), Zhansheng Zhang (Author), Xin Yao (Author), Dong Fang (Author), Songqiang Xie (Author), Hua Sun (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Formononetin is one of the main active compounds of traditional Chinese herbal medicine Astragalus membranaceus. However, disposition of formononetin via sulfonation pathway remains undefined. Here, expression-activity correlation was performed to identify the contributing of SULT1A3 to formononetin...