On the Role of ROS and Glutathione in the Mode of Action Underlying Nrf2 Activation by the Hydroxyanthraquinone Purpurin

• Main Authors: Qiuhui Ren (Author), Wouter Bakker (Author), Sebastiaan Wesseling (Author), Hans Bouwmeester (Author), Ivonne M. C. M. Rietjens (Author)
• Format: Bog
• Udgivet: MDPI AG, 2023-08-01T00:00:00Z.
• Fag: article
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Purpurin is a major anthraquinone present in the roots of <i>Rubia cordifolia</i> (madder). Purpurin is known to activate Nrf2 (Nuclear transcription factor erythroid 2-related factor 2) EpRE (electrophile responsive element) mediated gene expression as a potential beneficial effect. Thi...