Activation of PERK/eIF2α/ATF4/CHOP branch of endoplasmic reticulum stress response and cooperation between HIF-1α and ATF4 promotes Daprodustat-induced vascular calcification

Introduction: Vascular calcification is accelerated in patients with chronic kidney disease (CKD) and increases the risk of cardiovascular events. CKD is frequently associated with anemia. Daprodustat (DPD) is a prolyl hydroxylase inhibitor for the treatment of CKD-associated anemia that enhances er...

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Main Authors: Andrea Tóth (Author), Gréta Lente (Author), Dávid Máté Csiki (Author), Enikő Balogh (Author), Árpád Szöőr (Author), Béla Nagy (Author), Viktória Jeney (Author)
Format: Book
Published: Frontiers Media S.A., 2024-07-01T00:00:00Z.
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3rd Floor Main Library

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