The Utility of Iron Chelators in the Management of Inflammatory Disorders

• Main Authors: C. Lehmann (Author), S. Islam (Author), S. Jarosch (Author), J. Zhou (Author), D. Hoskin (Author), A. Greenshields (Author), N. Al-Banna (Author), N. Sharawy (Author), A. Sczcesniak (Author), M. Kelly (Author), K. Wafa (Author), W. Cheliak (Author), B. Holbein (Author)
• Format: Book
• Published: Hindawi Limited, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Since iron can contribute to detrimental radical generating processes through the Fenton and Haber-Weiss reactions, it seems to be a reasonable approach to modulate iron-related pathways in inflammation. In the human organism a counterregulatory reduction in iron availability is observed during infl...