Clozapine Prevents a Decrease in Neurogenesis in Mice Repeatedly Treated With Phencyclidine

• Main Authors: Kenji Maeda (Author), Haruhiko Sugino (Author), Tsuyoshi Hirose (Author), Hisashi Kitagawa (Author), Taku Nagai (Author), Hiroyuki Mizoguchi (Author), Kazuhiro Takuma (Author), Kiyofumi Yamada (Author)
• Format: Book
• Published: Elsevier, 2007-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

It has recently been suggested that neurogenesis in the dentate gyrus is decreased in schizophrenia and this phenomenon may contribute to the pathogenesis of the disorder. Since repeated administration of psychostimulants such as phencyclidine (PCP), MK-801, and methamphetamine (METH) induces schizo...