Accuracy of chimeric proteins in the serological diagnosis of chronic chagas disease - a Phase II study.

• Main Authors: Fred Luciano Neves Santos (Author), Paola Alejandra Fiorani Celedon (Author), Nilson Ivo Tonin Zanchin (Author), Wayner Vieira de Souza (Author), Edimilson Domingos da Silva (Author), Leonardo Foti (Author), Marco Aurélio Krieger (Author), Yara de Miranda Gomes (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2017-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:The performance of current serologic tests for diagnosing chronic Chagas disease (CD) is highly variable. The search for new diagnostic markers has been a constant challenge for improving accuracy and reducing the number of inconclusive results. METHODOLOGY/PRINCIPAL FINDINGS:Here, four c...