Cardiac STAT3 Deficiency Impairs Contractility and Metabolic Homeostasis in Hypertension

• Váldodahkkit: Raffaele Altara (Dahkki), Romain Harmancey (Dahkki), Sean P Didion (Dahkki), George W. Booz (Dahkki), Fouad Zouein (Dahkki), Fouad A Zouein (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Frontiers Media S.A., 2016-11-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Signal transducer and activator of transcription 3 (STAT3) protects the heart from acute ischemic stress. However, the importance of STAT3 to the heart in chronic stress, such as hypertension, is not known. To study this, we used cardiomyocyte-targeted STAT3 knockout (KO) mice and ANG II infusion by...