Cardiac STAT3 Deficiency Impairs Contractility and Metabolic Homeostasis in Hypertension

• मुख्य लेखकों: Raffaele Altara (लेखक), Romain Harmancey (लेखक), Sean P Didion (लेखक), George W. Booz (लेखक), Fouad Zouein (लेखक), Fouad A Zouein (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2016-11-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Signal transducer and activator of transcription 3 (STAT3) protects the heart from acute ischemic stress. However, the importance of STAT3 to the heart in chronic stress, such as hypertension, is not known. To study this, we used cardiomyocyte-targeted STAT3 knockout (KO) mice and ANG II infusion by...