Infection-Induced Elevated Plasma Perampanel in a Patient with Hemimegalencephaly

• Main Authors: Yuya Kinoshita (Author), Hiroe Ueno (Author), Hirofumi Kurata (Author), Chizuru Ikeda (Author), Erika Hori (Author), Takumi Okada (Author), Tomoyuki Shimazu (Author), Isao Fujii (Author), Makoto Matsukura (Author), Hoseki Imamura (Author)
• Format: Book
• Published: Hindawi Limited, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Perampanel is a noncompetitive, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid glutamate receptor antagonist. Herein, we report a case of increased perampanel plasma concentration and impaired consciousness triggered by an infection. The patient had refractory epilepsy associated with hemimega...