Immunohistochemical Evaluation of the Hedgehog Route as a Potential Prognostic Factor in Hepatocellular Carcinoma

• Main Authors: João Paulo Imperes Lira (Author), Jesus Junior Faria Rosa (Author), Ronniel Morais Albuquerque (Author), Thiago Almeida Pereira (Author), Paula Vieira Teixeira Vidigal (Author)
• Format: Book
• Published: Sociedade Brasileira de Patologia Clínica, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACT Introduction Hepatocellular carcinoma (HCC) is the most common primary malignant neoplasm in the liver. HCC develops gradually from multiple stages that control proliferation and apoptosis. In hepatocarcinogenesis, multiple signaling pathways were already described, such as the Hedgehog pat...