Hesperidin inhibits the epithelial to mesenchymal transition induced by transforming growth factor-β1 in A549 cells through Smad signaling in the cytoplasm

• Egile Nagusiak: Zhouxin Ren (Egilea), Junling Shen (Egilea), Xiaofeng Mei (Egilea), Haoran Dong (Egilea), Jiansheng Li (Egilea), Haibin Yu (Egilea)
• Formatua: Liburua
• Argitaratua: Universidade de São Paulo, 2019-10-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Hesperidin, a natural compound, suppresses the epithelial-to-mesenchymal transition through the TGF-β1/Smad signaling pathway. However, studies on the detailed effects and mechanisms of hesperidin are rare. The present study showed that, for A549 alveolar epithelial cells, the anti-proliferative eff...