Anti-Fibrotic Activity of an Antimicrobial Peptide in a Drosophila Model

• Váldodahkkit: Dilan Khalili (Dahkki), Christina Kalcher (Dahkki), Stefan Baumgartner (Dahkki), Ulrich Theopold (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Karger Publishers, 2021-05-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Fibrotic lesions accompany several pathological conditions, including tumors. We show that expression of a dominant-active form of the Ras oncogene in Drosophila salivary glands (SGs) leads to redistribution of components of the basement membrane (BM) and fibrotic lesions. Similar to several types o...