Hypotonic Stress Increases Efficacy of Rilmakalim, but Not Pinacidil, to Activate ATP-Sensitive K+ Current in Guinea Pig Ventricular Myocytes

• Main Authors: Ivan Kocić (Author), Yuji Hirano (Author), Masayasu Hiraoka (Author)
• 格式: 图书
• 出版: Elsevier, 2004-01-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

The aim of this study was to investigate the influence of hypotonic challenge on the effects of potassium channel openers (PCO), rilmakalim and pinacidil, on activation of the ATP-sensitive K+ current. The whole cell configuration of the patch-clamp technique was applied to guinea pig ventricular my...