Protein Kinase A-Dependence of the Supraspinally Mediated Analgesic Effects of Gabapentin on Thermal and Mechanical Hypersensitivity
Abstract.: We have recently shown that gabapentin generates protein kinase A (PKA)-dependent presynaptic inhibition of GABAergic synaptic transmission in locus coeruleus (LC) neurons only under neuropathic states. To verify behaviorally this in vitro electrophysiological finding, the PKA inhibitor H...
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| Principais autores: | , , , |
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| Formato: | Livro |
| Publicado em: |
Elsevier,
2009-01-01T00:00:00Z.
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| Número de Chamada: |
A1234.567 |
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| Cópia 1 | Disponível |