Pharmacokinetics and exposure-safety relationship of ciprofol for sedation in mechanically ventilated patients in the intensive care unit

• Glavni autori: Lu Liu (Autor), Kun Wang (Autor), Zhongyi Sun (Autor), Pangke Yan (Autor), Mengyue Hu (Autor), Xiao Liu (Autor), Meixia Chen (Autor), Nan Wu (Autor), Xiaoqiang Xiang (Autor)
• Format: Knjiga
• Izdano: Wiley, 2024-05-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Abstract Ciprofol (HSK3486) is a newly developed, highly selective γ‐aminobutyric acid‐A (GABAA) receptor potentiator that is recently approved for a new indication of sedation for patients in the intensive care unit (ICU) in China. This analysis aimed to characterize the population pharmacokinetics...