Relative bioavailability and food effect study of an oral suspension of alectinib in healthy volunteers using venipuncture and capillary microsampling

• Main Authors: Stephanie N. Liu (Author), Priya Agarwal (Author), Katja Heinig (Author), Asim Datye (Author), Carolina Sturm‐Pellanda (Author), Andrea Crugnola (Author), Marc Arca (Author), Dale Miles (Author)
• Format: Book
• Published: Wiley, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Alectinib, approved as 150 mg capsules for the treatment of adults with advanced ALK‐positive non‐small cell lung cancer, is being assessed in children with ALK‐positive solid and central nervous system tumors. An ad hoc pediatric‐friendly suspension of alectinib, prepared from capsule cont...