Effects of Polyphenols on P-Glycoprotein (ABCB1) Activity

• Main Authors: Kuljeet Singh (Author), Szabolcs Tarapcsák (Author), Zsuzsanna Gyöngy (Author), Zsuzsanna Ritter (Author), Gyula Batta (Author), Rosevalentine Bosire (Author), Judit Remenyik (Author), Katalin Goda (Author)
• Format: Book
• Published: MDPI AG, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

P-glycoprotein (Pgp, ABCB1) is a member of one of the largest families of active transporter proteins called ABC transporters. Thanks to its expression in tissues with barrier functions and its broad substrate spectrum, it is an important determinant of the absorption, metabolism and excretion of ma...