Is Polymorphism in the Apoptosis and Inflammatory Pathway Genes Associated With a Primary Response to Anti-TNF Therapy in Crohn's Disease Patients?

• मुख्य लेखकों: Michal Walczak (लेखक), Liliana Lykowska-Szuber (लेखक), Marianna Plucinska (लेखक), Kamila Stawczyk-Eder (लेखक), Oliwia Zakerska-Banaszak (लेखक), Piotr Eder (लेखक), Iwona Krela-Kazmierczak (लेखक), Michal Michalak (लेखक), Marek Zywicki (लेखक), Wojciech M. Karlowski (लेखक), Marlena Szalata (लेखक), Agnieszka Dobrowolska (लेखक), Ryszard Slomski (लेखक), Marzena Skrzypczak-Zielinska (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2020-08-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Anti-tumor necrosis factor (TNF) therapy is used for the induction and maintenance of remission in Crohn's disease (CD) patients. However, primary nonresponders to initial treatment constitute 20%-40% of cases. The causes of this phenomenon are still unknown. In this study, we aimed to determin...