Is Polymorphism in the Apoptosis and Inflammatory Pathway Genes Associated With a Primary Response to Anti-TNF Therapy in Crohn's Disease Patients?

• 主要な著者: Michal Walczak (著者), Liliana Lykowska-Szuber (著者), Marianna Plucinska (著者), Kamila Stawczyk-Eder (著者), Oliwia Zakerska-Banaszak (著者), Piotr Eder (著者), Iwona Krela-Kazmierczak (著者), Michal Michalak (著者), Marek Zywicki (著者), Wojciech M. Karlowski (著者), Marlena Szalata (著者), Agnieszka Dobrowolska (著者), Ryszard Slomski (著者), Marzena Skrzypczak-Zielinska (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2020-08-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Anti-tumor necrosis factor (TNF) therapy is used for the induction and maintenance of remission in Crohn's disease (CD) patients. However, primary nonresponders to initial treatment constitute 20%-40% of cases. The causes of this phenomenon are still unknown. In this study, we aimed to determin...